If you suffer from nerve pain, you know how debilitating it can be. Nerve pain, also known as neuropathy, can cause a wide range of symptoms, including tingling, numbness, and burning sensations. This normally happens to elderly people due to their age. A study was made with elderly people from a nursing home towards the prevalence of neuropathic pain and 14.6% of the elders were said to felt or have neuropathic pain of some sort/
While there are many treatments available, including prescription medications, some people prefer to use over-the-counter nerve pain relief creams. These creams can help to alleviate pain and discomfort without the need for a prescription. It is important to note that while nerve pain relief creams can be effective for some people, they may not work for everyone. It is also important to talk to your doctor before using any new treatment, especially if you have any underlying medical conditions or are taking any medications. With that in mind, let’s take a look at some of the best nerve pain relief creams available on the market today.
Understanding Nerve Pain
If you are experiencing nerve pain, you know how debilitating it can be. It can interfere with your daily activities, making it difficult to work, sleep, or even enjoy your favorite hobbies. In this section, we will discuss the causes and symptoms of nerve pain.
Causes of Nerve Pain
Nerve pain can be caused by a variety of factors, including injury, infection, and chronic diseases such as diabetes. Injuries that damage the nerves, such as a herniated disc or a pinched nerve, can cause nerve pain. Infections such as shingles or HIV can also lead to nerve pain. Chronic diseases such as diabetes can cause nerve damage over time, leading to nerve pain.
Symptoms of Nerve Pain
Nerve pain can manifest in different ways, depending on the location and severity of the nerve damage. Some common symptoms of nerve pain include:
- Burning or tingling sensations
- Numbness or weakness in the affected area
- Shooting or stabbing pain
- Sensitivity to touch or temperature changes
If you are experiencing any of these symptoms, it is important to seek medical attention. Your healthcare provider can help diagnose the underlying cause of your nerve pain and recommend appropriate treatment options.
Criteria for Choosing a Nerve Pain Relief Cream
When choosing a nerve pain relief cream, there are several factors to consider to ensure that you get the best possible results. Here are some key criteria to keep in mind:
Active Ingredients
The active ingredients in a nerve pain relief cream are the most important factor to consider. Some common active ingredients include capsaicin, lidocaine, and menthol. Capsaicin is a natural substance found in chili peppers that can help relieve pain by blocking nerve signals. Lidocaine is a local anesthetic that can numb the area where it is applied. Menthol is a cooling agent that can help soothe the skin and reduce inflammation.
Different active ingredients may work better for different types of nerve pain, so it’s important to choose a cream that contains the right active ingredients for your specific symptoms.
Cream Base and Consistency
The cream base and consistency can also affect how well the cream works and how easy it is to apply. Some creams are thick and greasy, while others are lightweight and absorb quickly. Creams that are too thick may be difficult to apply and may leave a residue on your skin, while creams that are too thin may not provide enough coverage.
It’s important to choose a cream that has a consistency that works well for your needs. If you have sensitive skin, you may want to choose a cream that is fragrance-free and hypoallergenic.
Absorption Rate
The absorption rate of a nerve pain relief cream can also affect how well it works. Creams that absorb quickly may provide faster relief, while creams that take longer to absorb may provide longer-lasting relief.
It’s important to choose a cream that has an absorption rate that works well for your needs. If you need fast relief, you may want to choose a cream that absorbs quickly. If you need longer-lasting relief, you may want to choose a cream that takes longer to absorb.
Potential Side Effects
Finally, it’s important to consider the potential side effects of a nerve pain relief cream. Some creams may cause skin irritation, redness, or itching. Others may cause more serious side effects, such as allergic reactions or breathing difficulties.
Before using a nerve pain relief cream, it’s important to read the label carefully and follow the instructions for use. If you experience any side effects, stop using the cream immediately and contact your healthcare provider.
Top Recommended Nerve Pain Relief Creams
If you’re looking for relief from nerve pain, there are a variety of creams available that can help. Here are some of the top recommended nerve pain relief creams:
Over-the-Counter Options
Penetrex Joint & Muscle Therapy Cream
This cream contains Arnica, MSM, and Boswellia Serrata, which are known for their anti-inflammatory properties. It is also infused with Vitamin B6, which can help to reduce nerve pain. Penetrex is a popular choice among those with nerve pain, and many users report significant pain relief.
- Giftable 2-Ounce Size – Ideal Stocking Stuffer & Trusted Daily Relief for Back, Neck, Knee, Shoulder & Hand Discomfort – Non-NSAID Formula. Penetrex provides targeted support for common problem areas including lower back, stiff neck, achy knees, shoulder tension, and hand soreness. Formulated without NSAIDs (non-steroidal anti-inflammatory drugs) for those seeking natural alternatives to oral medications or medicated patches for routine joint and muscle strain.
- Professional-Grade Ingredients: Arnica, MSM, Vitamin B6 & Boswellia for Enhanced Support. Enhanced with clinically-studied botanicals and nutrients recognized for their soothing properties. Arnica montana has been used traditionally for centuries, while MSM (Methylsulfonylmethane), Vitamin B6, and Boswellia Serrata work synergistically to support muscles and joints experiencing occasional discomfort from exercise, repetitive motion, or daily activity.
- Fast-Absorbing, Non-Greasy Cream – No Menthol Smell, Won't Stain Clothing. Lightweight, fast-penetrating formula absorbs quickly into skin without leaving oily residue, sticky feeling, or transferring to clothes or bed sheets. Unlike menthol-based products with strong medicinal odors, Penetrex is fragrance-free with no overpowering scent, making it ideal for use anytime – at work, before bed, or during your daily routine.
Bengay Lidocaine Cream
Bengay Lidocaine Cream is a topical analgesic that contains 4% lidocaine, which can help to numb the area and provide relief from nerve pain. This cream is also infused with menthol, which can provide a cooling sensation to help soothe the area.
- TOPICAL PAIN RELIEF: 3-ounce tube of Bengay Lidocaine Topical Pain Relief Cream with a tropical jasmine scent for temporary relief of muscle and joint pain with numbing power to desensitize nerves
- POWERFUL LIDOCAINE CREAM: Bengay pain relief cream is made with maximum strength OTC 4% lidocaine HCI as an active ingredient to work to desensitize nerves and deliver numbing relief for muscle pain and joint pain
- DESENSITIZE NERVES: This soothing pain relief cream is formulated with a non-greasy formula, so it won't leave behind any residue. It can be used to help combat upper & lower back pain, neck pain, shoulder pain, knee pain, elbow pain, & joint pain
| What We Like: | What We Don’t Like: |
Maximum Strength Numbing Relief: Bengay’s Lidocaine HCl formula provides maximum numbing relief for muscle and joint pain. Non-Greasy Formula: Unlike some competitors, Bengay’s formula is non-greasy, leaving no residue on skin or clothing. Pleasant Scent: Infused with tropical jasmine scent, Bengay’s Lidocaine Cream offers a pleasant aroma without a medicinal smell. Versatile Application: Effective for pain relief in various body parts, including back, neck, shoulders, knees, elbows, hands, and wrists. Doctor Recommended: Bengay, a trusted OTC brand, is recommended by doctors for topical pain relief. | Cost: Bengay’s Lidocaine Cream is a bit pricey compared to some other pain relief creams on the market. However, many users find that the relief it provides is worth the cost. Scent may not be for everyone: While many users enjoy the tropical jasmine scent, some may find it too strong or overwhelming. Limited packaging options: Bengay’s Lidocaine Cream is only available in a 3 oz. tube. If you’re looking for a larger or smaller size, you may need to consider other products. |
Aspercreme Lidocaine Cream
Aspercreme Lidocaine Cream is another topical analgesic that contains 4% lidocaine. It also contains aloe vera, which can help to soothe the skin. This cream is a good choice for those with sensitive skin.
- Contains one (1) 4.3-oz. tube of Aspercreme Pain Relief Cream With Max-Strength Lidocaine and Moisturizing Aloe
- Fast-Acting Relief: Experience rapid and lasting pain relief with max-strength 4% lidocaine topical numbing cream, designed to target nerves and numb away pain
- Non-greasy Formula: Fragrance-free Aspercreme moisturizes and relieves without greasy residue or strong odor
| What We Like: | What We Don’t Like: |
Fast-Acting Relief: Aspercreme with Lidocaine works within minutes for hours of numbing relief, ideal for those needing quick pain alleviation. Enhanced Pain Targeting: With 4% lidocaine, it targets more pain receptors, effectively numbing minor pains without irritation or burning, suitable for sensitive skin. Targets Joints and Muscles: Designed for arthritis, backaches, muscle strains, and sprains, Aspercreme joint and muscle pain cream offer versatile relief for various pains. Odor-Free and Non-Greasy: Unlike many competitors, Aspercreme with Lidocaine is odor-free and non-greasy, ensuring ease of use without unpleasant smells or residue. Over-the-Counter Availability: Aspercreme patches, creams, lotions, roll-ons, and gels with lidocaine are accessible without a prescription, facilitating easy access to pain relief. | Limited pain relief: While Aspercreme with Lidocaine is fast-acting and targets more pain receptors, it may not provide as much pain relief as other prescription-grade options for more severe pain. Price: Some users may find the price of Aspercreme with Lidocaine to be higher than other over-the-counter pain relief creams, but the convenience of being able to purchase it without a prescription may outweigh the cost. |
Prescription-Strength Creams
Voltaren Gel
Voltaren Gel is a prescription-strength topical gel that contains diclofenac, which is a nonsteroidal anti-inflammatory drug (NSAID). It can help to reduce inflammation and provide relief from nerve pain. Voltaren Gel is a good choice for those with arthritis pain, as well as nerve pain.
- One 3.5 oz/100 g tube and one 0.71 oz/20 g travel size tube of Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief- Easy flip cap that can be opened with your palm, fingers, or even with just one hand; packaging may vary
- Number 1 Doctor Recommended topical pain relief brand
- Clinically Proven to relieve arthritis pain, improve mobility and reduce stiffness, aches and pains to provide prescription strength arthritis pain relief
| What We Like: | What We Don’t Like: |
Powerful Pain Relief: Voltaren Arthritis Pain Gel is clinically proven to alleviate arthritis pain, enhance mobility, and diminish stiffness, aches, and pains, offering prescription-strength relief without pills. Deep Penetration: Diclofenac sodium topical gel penetrates deeply to target arthritis pain at its source of inflammation, addressing the root cause rather than just masking symptoms. Pill-Free Alternative: Voltaren, a nonsteroidal anti-inflammatory gel, combines the benefits of cream and gel for arthritis pain management, providing an effective alternative to pills with potential side effects. Convenient Sizes: Available in 3.5 oz/100 g and 0.71 oz/20 g sizes, making it portable for on-the-go use. Doctor Recommended: Voltaren is the top doctor-recommended topical pain relief brand, ensuring confidence in its effectiveness backed by medical professionals. | Eccentric Directions: Some users have reported that the product directions seem slightly eccentric, with illustrations showing that you can use it on three areas at the same time but no more. This may cause confusion for some users. Sticky Texture: Some users have reported that the product has a slightly sticky texture, which can be uncomfortable or unpleasant to apply. Limited Pain Relief: While the product does provide some pain relief, some users have reported that it does not work as well as they had hoped and may not be effective for all types of arthritis pain. |
When to Consult a Healthcare Professional
While over-the-counter nerve pain relief creams can be effective for mild to moderate pain, it is important to know when to seek medical attention.
If you experience severe or persistent pain, numbness, or tingling, or if your symptoms worsen over time, it is recommended that you consult a healthcare professional. This is especially important if you have an underlying medical condition or are taking prescription medications.
Your healthcare provider can perform a physical exam and order diagnostic tests to determine the underlying cause of your nerve pain. Depending on the cause, they may recommend a prescription-strength medication or refer you to a specialist for further treatment.
In addition to medication and other treatments, your healthcare provider may recommend lifestyle changes such as exercise, stress management, and a healthy diet to help manage your nerve pain. It is important to follow your healthcare provider’s recommendations and attend all follow-up appointments to ensure the best possible outcome.
Remember, while nerve pain can be challenging to manage, there are many effective treatments available. By working with your healthcare provider and making positive lifestyle changes, you can take control of your pain and improve your quality of life.
Frequently Asked Questions
What are the most effective over-the-counter creams for nerve pain relief?
When it comes to over-the-counter creams for nerve pain relief, the most effective ones are those that contain active ingredients like lidocaine, capsaicin, and menthol. These ingredients work by numbing the nerves and reducing pain signals to the brain. Some of the best creams for nerve pain relief that you can find at your local drugstore include Aspercreme with Lidocaine, Biofreeze, and Icy Hot.
Which ingredients should I look for in a cream to alleviate neuropathic pain?
When looking for a cream to alleviate neuropathic pain, you should look for ingredients that have been clinically proven to be effective. Some of the most commonly used ingredients in neuropathic pain creams include lidocaine, capsaicin, menthol, and diclofenac. These ingredients work by blocking pain signals and reducing inflammation in the affected area.
Are there any prescription creams specifically designed for treating nerve pain?
Yes, there are prescription creams that have been specifically designed for treating nerve pain. These creams usually contain higher concentrations of active ingredients than over-the-counter creams and are only available with a prescription from a doctor. Some of the most commonly prescribed nerve pain creams include Lidoderm, Voltaren Gel, and Pennsaid.
Can topical creams provide immediate relief for nerve pain?
Topical creams can provide immediate relief for nerve pain, but the duration of the relief varies depending on the severity of the pain and the type of cream used. Some creams provide instant relief that lasts for a few hours, while others take longer to work but provide longer-lasting relief. It’s important to follow the instructions on the cream and use it as directed to get the best results.
What is the strongest topical anesthetic for nerve pain management?
Lidocaine is considered the strongest topical anesthetic for nerve pain management. It works by blocking pain signals from the affected area and numbing the nerves. Lidocaine creams are available over-the-counter and by prescription, and they are commonly used to treat nerve pain caused by shingles, diabetic neuropathy, and other conditions.
How do creams for nerve pain in specific areas like the feet or back differ?
Creams for nerve pain in specific areas like the feet or back differ in terms of their active ingredients and the way they are formulated. For example, creams designed for foot pain often contain ingredients like arnica and menthol, which can help reduce inflammation and soothe sore muscles. On the other hand, creams designed for back pain may contain ingredients like capsaicin and lidocaine, which work by numbing the nerves and reducing pain signals to the brain. It’s important to choose a cream that is specifically designed for the area where you are experiencing nerve pain.
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Disclaimer: Last update on 2026-01-07 / Affiliate links / Images from Amazon Product Advertising API.
This content is provided solely for educational reasons and should not be seen as medical guidance. It’s important to consult with a healthcare expert prior to making any changes to your health regimen, including dietary adjustments or the use of supplements.
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